Comparison of high flow nasal cannula versus standard oxygen therapy assisted sedation during endoscopic retrograde cholangiopancreatography
Overview
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Incidence of hypoxemia spo2 less than 95% for 10 seconds and severe hypoxemia spo2 less than 90% for 10seconds during procedural time
Overview
Brief Summary
ERCP is a common diagnostic and therapeutic procedure often require sedation. The incidence of hypoxemia noted during ERCP under sedation presumably because lengthy procedure, endoscopist share common airway and is performed in semiprone or pronr postion. The choice of oxygen method during sedation play a crucial role in safety and outcomes as well as patient comfort.
Use of HFNC is widened to critical care and day care procedures in non operating room anesthesia settings under sedation.
Very few similar studies conducted in Indian population .
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 70.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •ASA Physical status class I-III , schedule for elective ERCP under sedation.
Exclusion Criteria
- •Age less than 18yrs or more than 70yrs with coexisting respiratory, cardiac illness, dementia, cognitive disorder, pregnancy, allergic to Propofol and Fentanyl, anticipated difficult intubation , tracheostomized, emergency ERCP.
Outcomes
Primary Outcomes
Incidence of hypoxemia spo2 less than 95% for 10 seconds and severe hypoxemia spo2 less than 90% for 10seconds during procedural time
Time Frame: At baseline and T1,5,10,15,20,30,45,60,75(minutes) and PACU
Secondary Outcomes
- Total Propofol consumption(At end of procedure in PACU)
- Need of assisted ventilation(During procedure in between when required & requirement episodes will be recorded)
- Airway manipulation(During procedure & episodes will be recorded)
- Endoscopist & Patient satisfaction(At end of Procedure)
- Total procedural duration(At end of procedure)
Investigators
Dr D R Famara
Army Hospital Research and Referral, Delhi