An effect of azithromycin for exacerbation in asthma patients with obesity: the protocol for a multi-center, prospective single-arm intervention study
- Conditions
- Asthma
- Registration Number
- JPRN-UMIN000048438
- Lead Sponsor
- Saga University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Not provided
Exclusion criteria will be: patients whose aspartate aminotransferase or alanine aminotransferase at more than 100 IU/L, creatinine at 2.0 mg/dL, who have life threatened arrhythmia or paroxysmal tachycardia at more than 100 times per minute of heart rate, who had been admitted by acute myocardial infarction or heart failure in previous year, who diagnosed malignancy in previous 5 years except for complete remission after the treatment, who treated by macrolide antibiotics in previous 4 week and biologics including omalizumab, mepolizumab, benralizumab, dupilumab in previous 8 weeks at initiation of the intervention of azithromycin in present study, whose QT interval requires correction for heart rate at more than 480 ms, who are pregnant or under breastfeeding, whose BMI at less than 25 kg/m2, and who decided ineligible for present study by researchers.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method