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Comparison of 2 drug combinations for sedation in cervical cancer patients undergoing radiotherapy

Phase 4
Conditions
Health Condition 1: O- Medical and Surgical
Registration Number
CTRI/2024/03/063806
Lead Sponsor
Ananta institute of medical sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Patients of cervical cancer scheduled for elective

brachytherapy

Patients aged between 20-70 years

ASA I, II

Exclusion Criteria

History of cardiovascular diseases e.g. ischaemic heart disease,conduction defects, etc.

History of compromised renal / hepatic / neuronal functions.

Uncontrolled hypertension and Diabetes

Pregnant or lactating women.

History alcohol, substance abuse, chronic use of analgesic and

sedatives, psychiatric disorders

Patients on b blocker or having persistent bradycardia with HR30

min

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Onset and recovery of sedationTimepoint: Baseline, 1,2,5,7,10,15,20,25 and 30 minutes.
Secondary Outcome Measures
NameTimeMethod
Intraoperative Haemodynamics (Heart <br/ ><br>Rate,Blood Pressure, Spo2, Respiratory rate) <br/ ><br>Post op recovery score (Modified Aldrete Score) <br/ ><br>Duration of analgesiaTimepoint: Baseline, 1, 2,5,7,10,15,20,25 & 30 minutes & then hourly for 6 hours.
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