The influence of vagal nerve stimulation on reward-based selective attentio
Withdrawn
- Conditions
- attentionreward sensitivity10039911
- Registration Number
- NL-OMON38674
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 15
Inclusion Criteria
Capability of giving informed consent - Patients implanted with a VNS device for the treatment of epilepsy - Age > 18 years
Exclusion Criteria
Incapability of participating in the experiments as judged by the investigators - Inability to turn off the stimulators for the duration of the experiment on clinical grounds
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Main parameters of interest are the reaction time differences in the visual<br /><br>search tasks, and alterations of perceived stimulus presentation onset. Both<br /><br>can be used as a measure to indicate the degree of influence of VNS on reward<br /><br>processing and selective attention. Previous and ongoing studies on healthy<br /><br>observers in our groups show a beneficial effect of monetary reward on reaction<br /><br>times in visual search tasks (Hickey et al. 2010) and perceived stimulus onset<br /><br>in the simultaneity judgement task. In the present study we aim to test both<br /><br>whether VNS changes these effects of monetary reward and whether stimulation<br /><br>could actually replace the monetary reward as source for the observed influence<br /><br>on selective attention. </p><br>
- Secondary Outcome Measures
Name Time Method <p>not applicable</p><br>