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Clinical Trials/NCT01457794
NCT01457794
Completed
N/A

OPUS(Optimal Well-being, Development and Health for Danish Children Through a Healthy New Nordic Diet) School Meal Study

Arne Astrup1 site in 1 country834 target enrollmentMay 2011

Overview

Phase
N/A
Intervention
Not specified
Conditions
Metabolic Syndrome X
Sponsor
Arne Astrup
Enrollment
834
Locations
1
Primary Endpoint
Concentration Performance
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

The aim of this randomized crossover study, is to investigate the effect of school meals based on a sustainable New Nordic Diet on growth, learning abilities, well-being, sleep quality, physical activity and risk markers of cardiovascular disease (CVD), type II diabetes and osteoporosis in 8-11 year old Danish school children.

The participating 3rd and 4th grades on 9 selected primary schools will be randomized to either start receiving New Nordic Diet school meals for 3 month(mo) or to eat their habitual school lunch for 3 mo and then crossover for additional 3 mo. All participants will be examined three times; at baseline, after 3 mo and after 6 mo.

Registry
clinicaltrials.gov
Start Date
May 2011
End Date
June 2012
Last Updated
9 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
Arne Astrup
Responsible Party
Sponsor Investigator
Principal Investigator

Arne Astrup

Professor, MD

University of Copenhagen

Eligibility Criteria

Inclusion Criteria

  • Pupils in 3rd and 4th grades
  • Primary Schools in the Zealand Region and Capital Region of Denmark
  • Schools with an available school kitchen, that can be approved by the food authorities
  • Schools where at least 60 % of the pupils in three or more classes signs up to participate in the Study

Exclusion Criteria

  • The children should not participate in a scientific study or have participated in a scientific study within the last 4 weeks. This, however depends on the character of the other study.
  • The children must not suffer from serious food allergies or food intolerance.
  • The children must not suffer from diseases or conditions that makes them ill-suited for participation in the study, eg. malabsorptive conditions or serious mental disorders
  • The Schools must not offer an well-established common meal plan, that provides most of the pupils with healthy food on a daily basis

Outcomes

Primary Outcomes

Concentration Performance

Time Frame: Change during 3 month of intervention compared with change during 3 month control period

Concentration Performance is assessed by means of a concentration test called the D2-test of Attention. Concentration Performance is derived from the number of correctly crossed out relevant items minus the errors of commission (confused).

Metabolic syndrome score

Time Frame: Change during 3 month of intervention compared with change during 3 month control period

The metabolic syndrome score is a continuous z-score based on individual z-scores for waist circumference (WC), mean arterial pressure (MAP), serum high density lipoprotein (HDL), Serum triglyceride (TG) and Homeostasis Model Assessment (HOMA) index. It´s an internal score meaning that the basis for the score is the distribution of values in this study population at baseline.

Secondary Outcomes

  • Mathematics proficiency(Change during 3 month of intervention compared with change during 3 month control period)
  • Early Cardiovascular Risk Markers(Change during 3 month of intervention compared with change during 3 month control period)
  • Use of ADHD medicine(Change during 3 month of intervention compared with change during 3 month control period)
  • Body weight and body mass index (BMI)(Change during 3 month of intervention compared with change during 3 month control period)
  • Iron status(Change during 3 month intervention compared with 3 month control period)
  • Inflammatory markers(Change during 3 month of intervention compared with change during 3 month control period)
  • General fatty acid composition of whole-blood(Change during 3 month of intervention compared with change during 3 month control period)
  • Sleep(Change during 3 month of intervention compared with change during 3 month control period)
  • Dietary intake(Change during 3 month of intervention compared with change during 3 month control period)
  • Illnesses and use of medicine(Change during 3 month of intervention compared with change during 3 month control period)
  • Reading proficiency(Change during 3 month of intervention compared with change during 3 month control period)
  • Learning(Change during 3 month of intervention compared with change during 3 month control period)
  • Other metabolic syndrome scores(Change during 3 month of intervention compared with change during 3 month control period)
  • Wellness(Change during 3 month of intervention compared with change during 3 month control period)
  • Physical activity(Change during 3 month of intervention compared with change during 3 month control period)
  • Fitness(Change during 3 month of intervention compared with change during 3 month control period)
  • Bone Health(Change during 3 month of intervention compared with change during 3 month control period)
  • Omega-3 index in whole-blood(Change during 3 month of intervention compared with change during 3 month control period)
  • Body composition(Change during 3 month of intervention compared with change during 3 month control period)
  • General fatty acid composition in whole-blood(Change during 3 month intervnetion compared with change during 3 month control period)
  • Appetite-regulating hormones(Change during 3 month of intervention compared with change during 3 month control period)
  • Vitamin D status(Baseline and change during 3 month of intervention compared with change during 3 month control period)
  • Attention - other measures(Change during 3 month of intervention compared with change during 3 month control period)

Study Sites (1)

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