Transdiagnostic study of Adverse Childhood Experiences in people with mental health problems - TrACE

MU Klinikum, Klinik für Psychiatrie und Psychotherapie0 sites550 target enrollmentJuly 10, 2024

Overview

Phase: N/A
Intervention: Not specified
Conditions: DSM-5: 300.4 Persistent depressive disordersICD-11: 6B41 Complex post-traumatic stress disorder
Sponsor: MU Klinikum, Klinik für Psychiatrie und Psychotherapie
Enrollment: 550
Status: Not Yet Recruiting
Last Updated: last year

No summary available.

Registry

who.int

Start Date

July 10, 2024

End Date

TBD

Last Updated

last year

Study Type

Observational

Sex

All

Sponsor

MU Klinikum, Klinik für Psychiatrie und Psychotherapie

•We will include participants with sufficient German language skills to perform all questionnaires, interviews and introductions of the behavioral paradigm. Patients have to meet diagnostic criteria of one of the following main diagnoses according to the DSM\-5: Diagnosis of a BPD (301\.83\), PDD (300\.4, 296\.2x, 296\.3x, 296\.3x), cPTSD (309\.9\), ED (296\.xx) or SSD (300\.82\). Healthy controls have to not fulfill a psychiatric disorder assessed within a screening.

•Clinical participants will be excluded if fulfilling DSM\-5 criteria of an active substance\-dependency (abstinence shorter than 6 months), a psychotic disorder or a bipolar I or II disorder or acute suicidality (as main or comorbid diagnosis). Participants will be screened and diagnosed by a trained clinician based on the DSM\-5 criteria (SCID\-5\-CV and SCID\-5\-PD interview). All Individuals will be excluded if having a current or past somatic or neurological disorders with effects on the brain or if currently pregnant. Non\-clinical participants will be excluded when having a history of a psychiatric disorder or a psychotherapeutic/psychopharmacological intervention within the last 10 years (reviewed by telephone screening and psychometric assessments). Participants with a regular (daily) current intake of benzodiazepines will be excluded due to confounding aspects for the experimental cyberball paradigm and the psychometric questionnaires.