Study on syndromes, tongue appearances, and prediction model of poor outcomes in patients with primary Sjogren's syndrome
Not Applicable
- Conditions
- primary Sjogren's syndrome
- Registration Number
- ITMCTR2200005984
- Lead Sponsor
- China-Japan Friendship Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Those who meet all of the following items can join the study:
1. Patients who meet 2016 ACR-EULAR Classification Criteria for primary Sjogrens Syndrome;
2. Age 18-75 years old;
3. Those who are conscious and able to communicate with others;
4. Those who signed informed consent before the start of the study, and are willing and able to complete questionnaires.
Exclusion Criteria
Those who meet one of the following items cannot be included in the study:
1. Pregnant or lactating women;
2. Mental patients;
3. Complicated with malignant tumor(s).
Study & Design
- Study Type
- Observational study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Tongue images;SS-related protein expression test;Immunoglobulin (IgA, IgM, IgG)of serum;C-reactive protein(CRP);Poor prognosis(ILD, thrombocytopenia, etc.);ESSDAI score;Erythrocyte sedimentation rate(ESR);Blood mononuclear cell RNA levels of methylation;Elements of TCM syndrome;
- Secondary Outcome Measures
Name Time Method ung CT scan;ESSPRI score;Renal function test;Fatigue VAS score;Liver function test;Blood routine test;Complements;Salivary flow rate;Autoantibody;Eye dryness VAS score;Labial salivary gland histopathology;Oral dryness VAS;Ultrasound Cardiogram(UCG);Schirmer's test of both eyes;Ultrasound of lumph nodes;Pain VAS score;