Break the Cycle: Prevention for Reducing Initiation Into Injection Drug Use
- Conditions
- Prevention and ControlSubstance Abuse, Intravenous
- Interventions
- Behavioral: Break the Cycle Intervention
- Registration Number
- NCT03502525
- Lead Sponsor
- New York University
- Brief Summary
Break the Cycle is a two-session, one-on-one, in-person intervention study designed to reduce the role persons who inject drugs (PWID) play initiating non-PWID into injection drug use. Study implementation is at two sites: New York City and Tallinn, Estonia. At baseline, quantitative data are collected via a structured computer-assisted personal interview, after which the intervention is conducted. At the 6-month follow-up, a modified version of the interview is repeated. The study uses a pre- versus post- design to compare the proportion of participants who helped with first injections, and who promoted injecting among non-PWID, in the 6 months prior to baseline with the proportions at the 6-month follow-up. Based on previous research on the intervention and on the underlying theory of motivational interviewing, increases in helping and promoting behaviors between baseline and follow-up would indicate that the intervention was not effective regardless of their effect size. Accordingly, the hypotheses that the intervention will produce reductions in assisting with first injections and engaging in injection promoting behaviors will be evaluated using one-tailed statistical tests. Break the Cycle intervention follows a motivational interviewing approach to enhance current injectors' motivation and skills to avoid helping with and promoting first injections among non-PWID. The intervention's core is a discussion between an interventionist and each participant on the following eight topics: the participant's first time injecting drugs; the participant's exposures to situations where helping with others' first injections is an option, and the extent to which they have helped; PWIDs' behaviors that might encourage non-PWID to inject for the first time; the range of risks associated with injection drug use; role-playing scenarios in which the participant develops behaviors and scripts for avoiding or refusing requests to initiate others into injection drug use; role- playing talking with other PWID about not encouraging non-PWID to start injecting; imparting safer injection practices when helping with a first injection seems like the best option; and receiving training in and using Narcan to reverse overdoses.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 400
- have injected drugs non-medically in the last 2 months
- able to provide informed consent
- age 18 or older
- able to participate in the interview and intervention in English (in New York City), Russian or Estonian (in Tallinn, Estonia)
- none
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Break the Cycle Intervention Break the Cycle Intervention All study participants are assigned to this experimental arm.
- Primary Outcome Measures
Name Time Method Number of participants helping with first injections 6 months Number of participants who helped persons who do not inject drugs with a first injection
- Secondary Outcome Measures
Name Time Method Number of participants who say positive things 6 months Number of participants who saying positive things about injecting to persons who do not inject drugs
Number of participants injecting in front of other people 6 months Number of participants injecting in front of people who do not inject drugs
Number of participants offering to give first injection 6 months Number of participants offering to give a first injection to persons who do not inject drugs
Trial Locations
- Locations (2)
New York University
🇺🇸New York, New York, United States
University of Tartu
🇪🇪Tallinn, Estonia