The Management of Neuroendocrine Tumours: A Nutritional Viewpoint.
- Conditions
- Neuroendocrine Tumours (NETs)Mediterranean Diet
- Registration Number
- NCT03592940
- Lead Sponsor
- Federico II University
- Brief Summary
Nutritional status in patients with neuroendocrine tumours (NETs), especially of gastroenteropancreatic origin, can be deeply affected by excessive production of gastrointestinal hormones, peptides, and amines, which can lead to malabsorption, diarrhoea, steatorrhea, and altered gastrointestinal motility. Besides, the surgical and/or medical management of NETs can lead to alteration of gastrointestinal secretory, motor, and absorptive functions, with both dietary and nutritional consequences. Indeed, disease-related malnutrition is a frequently encountered yet both underrecognized and understudied clinical phenomenon in patients with NETs, with substantial prognostic and socioeconomic consequences. Most of these conditions can be alleviated by a tailored nutritional approach, also with the aim of improving the efficacy of cancer treatments. In this setting, skilled nutritionists can play a fundamental role in the multidisciplinary health care team in NETs management and their presence should be recommended.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 100
- patients with neuroendocrine tumours (NETs)
- age>65 years
- < BMI 19 kg/m2
- vegetarians
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Adherence to Mediterranean Diet by Predimed Questionnaire December 2017 to June 2018 Validated 14-item tool of adherence to the Mediterranean diet, with three categories of adherence (≤5, low adherence, 6-9, average adherence and ≥10 points, high adherence)
- Secondary Outcome Measures
Name Time Method Body composition December 2017 to June 2018 BIA was performed using a BIA phase-sensitive system by experienced observers (an 800-µA current at a frequency single-frequency of 50 kHz BIA 101 RJL, Akern Bioresearch, Florence, Italy)
Related Research Topics
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Trial Locations
- Locations (1)
Silvia Savastano
🇮🇹Naples, Italy
Silvia Savastano🇮🇹Naples, Italy