Routine Minimally Invasive Thoracic Surgery Without Aspirin Withdraw

Not Applicable

Recruiting

• Conditions: Surgery; Aspirin Sensitivity
• Interventions: Procedure: Surgery Without Aspirin Withdraw

• Registration Number: NCT05511441
• Lead Sponsor: The Second Hospital of Shandong University

Brief Summary

Surgeons are increasingly confronted by patients on long-term low-dose acetylsalicylic acid (ASA). However, the perioperative management of these patients undergo non-cardiac surgery has not yet been clear. This single- arm study was to evaluate the safety of continuous use of ASA in the perioperative period in routine minimally thoracic surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-06-01
• Status Verified: 2022-08
• Study First Submitted: 2022-08-19
• Study First Submitted QC: 2022-08-19
• Last Update Submitted: 2022-08-19
• Study First Posted: 2022-08-23
• Last Update Posted: 2022-08-23
• Primary Completion: 2023-06-01
• Study Completion: 2025-06-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. patients with stage I-IIIa Non-small-cell Lung Cancer underwent radical resection or other benign lung lesions need Minimally Invasive Thoracic Surgery;
2. VATS and robotic surgery are both permitted;
3. cardio-pulmonary function can tolerate surgery.

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Exclusion Criteria

1. cardio-pulmonary function couldn't tolerate surgery;
2. high bleeding risk after the pre- operative evaluation.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Surgery Without Aspirin Withdraw	Surgery Without Aspirin Withdraw	Routine Minimally Invasive Thoracic Surgery Without Aspirin Withdraw

Primary Outcome Measures

Name	Time	Method
bleeding volume	on the surgery day	bleeding volume during surgery
surgery time	on the surgery day	total surgery time
postoperative drainage volume	within 7 days after surgery	chest drainage volume after surgery
postoperative drainage duration	within 7 days after surgery	chest drainage duration after surgery
postoperative hospitalization time	within 7 days after surgery	postoperative hospitalization time
postoperative complication rate	within 14 days after surgery	postoperative complication rate

Secondary Outcome Measures

Name	Time	Method
progression- free survival	within 5 years after surgery	progression- free survival
overall survival	within 10 years after surgery	overall survival

Trial Locations

Locations (1)

The Second Hospital Of Shandong Univercity; 🇨🇳 Jinan, Tianqiao, China