Double Dose Treatment: Corticosteroid injection therapy in arthritis.
Recruiting
- Conditions
- triamcinolontriamcinolonearthritisRAkenacort
- Registration Number
- NL-OMON21189
- Lead Sponsor
- Ziekenhuisgroep TwenteZilvermeeuw 1, 7609 PP Almelo +31(0)546 693 693
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 94
Inclusion Criteria
1. Arthritis patients, RA or other causes of chronic arthritis (not osteoarthritis and not gout) with an indication for local injection with corticosteroid due to active arthritis in knee joint;
2. Patients should have stable anti-arthritic co-medication.
Exclusion Criteria
1. Contraindication for local injection with corticosteroid (infection, relevant skin lesion, uncontrolled diabetes mellitus);
2. Chronic (>3 months) or current use of more than 10mg prednisolone or equivalent daily;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage of patients with sustained good response.
- Secondary Outcome Measures
Name Time Method 1. Percentage of patients with good response in symptomatic relief at individual weekly time points (at t = 2,3,4,5,6,7,8,9,10,11 weeks);<br /><br>2. Duration of response: Time lapsed between reaching good response;<br /><br>3. Time to good response;<br /><br>4. Asessment of arthritis activity by the trial physician;<br /><br>5. VAS pain at t = 0 and t = 12 weeks;<br /><br>6. Change of Range of Motion (ROM) on physical examination;<br /><br>7. Change of swelling on physical examination, as determined by the trial physician on T=0 and T=12 weeks;<br /><br>8. Change in patients health status.