Double dose treatment: Corticosteroid injection therapy in arthritis - DoDo
- Conditions
- To determine whether doubling the dose of triamcinolone injections in the treatment of arthritis in knee joints is more effective, both in number of responding patients and in duration of response (pain relief).
- Registration Number
- EUCTR2009-018187-10-NL
- Lead Sponsor
- Ziekenhuisgroep Twente
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- 0
•Arthritis patients, RA or other causes of chronic systemic arthritis (not osteoarthritis and gout) with an indication for local injection with corticosteroid in knee joint.
•Patients should have stable anti-arthritic co-medication, no changes will be made during the trial.
•Patients need to score at least ‘matig’ at a 5-point Likert scale at the initial questionnaire at t = 0 otherwise no significant difference can be measured.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
•Contraindication for local injection with corticosteroid (infection, relevant skin lesion, uncontrolled diabetes mellitus)
•Chronic (>3 months) or current use of more than 10mg prednisolone or equivalent daily.
•No informed consent.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method