Comparing the proportion of hypoxia in sedated adults undergoing OGD using TCI propofol versus intermittent boluses

Not Applicable

• Conditions: Respiratory; hypoxia

• Registration Number: PACTR201708002325400
• Lead Sponsor: The Aga Khan University, Nairobi

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-05-26
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 176

Inclusion Criteria

All ASA I and II adults aged 18 - 65 years scheduled to undergo non-emergent upper gastrointestinal endoscopy under sedation.

Exclusion Criteria

¿Known allergy to propofol, midazolam, soybean, egg.
¿Active respiratory tract infection.
¿History or indicator of large airway compromise e.g. obstructive sleep apnoea, COPD, presence of stridor, or known history of difficult bag-valve-mask ventilation.
¿Patients requiring additional types of sedative agents to achieve optimal sedation.
¿History of chronic exposure to sedative medication.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the proportion of hypoxia between the two study groups

Secondary Outcome Measures

Name	Time	Method
To compare the proportion of hypotension and bradycardia between the two study groups