Echocardiographic findings and cardiovascular outcomes of children with MIS-C and Kawasaki disease at a year follow-up: a prospective multicenter study
Recruiting
- Conditions
- Incidence of myocarditis and cardiac dysfunction in children with MIS-C was initially reported of 23-40%. While, the incidence of cardiac dysfunction or cardiovascular collapse associated with KD was reported as 5% in the 2017 KD guideline. However, long term data of detailed echocardiographic assessment of ventricular dysfunction, fate of coronary changes and MACE report in MIS-C is lack.MIS-C, Multisystem inflammatory syndrome in children, ventricular dysfunction, coronary artery, Kawasaki disease, long term
- Registration Number
- TCTR20230414003
- Lead Sponsor
- /A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 58
Inclusion Criteria
1. Pediatric patients who has been diagnosed with MIS-C or Kawasaki disease and regular follow up at Siriraj, Saraburi and Chonburi Hospital at least 1 year and
2. Echocardiographic examinations to assess LV function and coronary arteries were performed at the time of diagnosis, 2 weeks, 4-8 weeks following diagnosis, 1 year following diagnosis
Exclusion Criteria
Patients who had other congenital heart disease, myocardial disease, coronary anomaly, history of arrhythmia prior to diagnosis of MIS-C or KD
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ventricular dysfunction 1 year echocardiographic assessment; EF strain, DD, 3D
- Secondary Outcome Measures
Name Time Method coronary abnormality 1 year echocardiographic assessment: presence of coronary ectasia or aneurysms