Effect of Temperament, Anxiety and Depression on Immuninity in Colorectal Cancer Patients.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Temperament in non-metastatic colorectal cancer patients
研究概览
简要总结
Aim of the study is to evaluate if Temperament, Anxiety and Depression can affect Immunity and influence Survival in Colorectal Cancer Patients
详细描述
120 prospective patients, with non-metastatic colorectal cancer, will be evaluated with questionnaires and auto-questionnaires in order to assess temperament, anxiety and depression. The immunity status will be assessed by a blood sample with the aim to evaluate cell-mediated immunity.
Survivall will be related to level of anxiety/temperament/depression and cell-mediated immunity.
Univariate and multivariate model analisys will be performed in order to evaluate if anxiety/temperament/depression and cell-mediated immunity can be considered as prognostic factors.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosis of non-metastatic colorectal cancer
排除标准
- •previous other primary malignancies immunodepression diagnosis of major deppression diagnosis of anxiety/depression syndrome
结局指标
主要结局
Temperament in non-metastatic colorectal cancer patients
时间窗: 24 months
Evaluation if Temperament can be considered as dependent or indipendent prognostic factor for survival in non-metastatic colorectal cancer patients
次要结局
未报告次要终点
研究者
Marco La Torre
Medical Doctor, PhD
University of Roma La Sapienza