Effect of Temperament, Anxiety and Depression on Immuninity in Colorectal Cancer Patients. Effetti Del Temperamento, Dell'Ansia e Della Depressione Sulla Sopravvivenza Globale e Sulla Risposta Immunitaria Del Paziente Affetto da Adenocarcinoma Colo-Rettale.
- Conditions
- DepressionTemperamentColorectal CancerAnxiety
- Registration Number
- NCT01433146
- Lead Sponsor
- University of Roma La Sapienza
- Brief Summary
Aim of the study is to evaluate if Temperament, Anxiety and Depression can affect Immunity and influence Survival in Colorectal Cancer Patients
- Detailed Description
120 prospective patients, with non-metastatic colorectal cancer, will be evaluated with questionnaires and auto-questionnaires in order to assess temperament, anxiety and depression. The immunity status will be assessed by a blood sample with the aim to evaluate cell-mediated immunity.
Survivall will be related to level of anxiety/temperament/depression and cell-mediated immunity.
Univariate and multivariate model analisys will be performed in order to evaluate if anxiety/temperament/depression and cell-mediated immunity can be considered as prognostic factors.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 120
diagnosis of non-metastatic colorectal cancer
previous other primary malignancies immunodepression diagnosis of major deppression diagnosis of anxiety/depression syndrome
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Temperament in non-metastatic colorectal cancer patients 24 months Evaluation if Temperament can be considered as dependent or indipendent prognostic factor for survival in non-metastatic colorectal cancer patients
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
"Sapienza" University of Rome
🇮🇹Rome, Italy