MOSE to Improve the Diagnostic Accuracy During EUS-guided FNA Using a 19-gauge Needle for Solid Lesions
- Conditions
- Solid Tumor
- Registration Number
- NCT03130140
- Lead Sponsor
- Chinese University of Hong Kong
- Brief Summary
The technique of macroscopic on-site evaluation (MOSE) has recently been advocated for estimating the adequacy of a core specimen for histological diagnosis during EUS-FNA using a 19-gauge needle. How it compares to the conventional technique of tissue acquisition during EUS-FNA is uncertain.
The objective of this study is to evaluate the quantity and quality of tissue, and the diagnostic ability of MOSE when compared with the conventional combined histologic-cytologic analysis.
- Detailed Description
To evaluate the quantity and quality of tissue, and the diagnostic ability of MOSE when compared with the conventional combined histologic-cytologic analysis in a randomized controlled study.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 244
- Consecutive patients (aged between 18 and 80 years) referred for EUS-guided tissue acquisition for intestinal or extra-intestinal solid lesions more than 2cm in the largest diameter would be included.
- Patients with coagulopathy, altered anatomy, contraindications for conscious sedation, pregnancy and those who cannot provide informed consent would be excluded.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Diagnostic yield: Proportion of patients with adequate tissue for diagnosis obtained by EUS FNA 4 weeks proportion of patients with adequate tissue for diagnosis obtained by EUS FNA
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Chinese University of Hong Kong
🇭🇰Hong Kong, Hong Kong
Chinese University of Hong Kong🇭🇰Hong Kong, Hong Kong