Intraoperative detection of tumor tissue in peritoneal carcinomatosis of colorectal origin using a VEGF-targeted Optical Fluorescent Imaging Tracer. A single centre feasibility study (HI-LIGHT study NL45588)

Not provided0 sites10 target enrollmentStarted: TBDLast updated: February 28, 2024

Conditions

Trial Snapshot

•Age >=18 years, patients with histopathological proven peritoneal carcinomatosis from colorectal origin who are scheduled to undergo the HIPEC procedure, patient is considered to be mentally and physically fit for the HIPEC procedure as judged by the responsible physician, WHO performance score 0-2, signed written informed consent.

•Concomitant malignancies, except for adequately treated basocellular carcinoma of the skin or in situ carcinoma of the cervix uteri. Subjects with prior malignancies must be disease-free for at least 5 years. Distance metastasis (liver / lungs), Medical or psychiatric conditions that compromise the patient¡¯s ability to give informed consent. Concurrent uncontrolled medical conditions. Pregnancy or breast feeding. Clinically significant (i.e. active) cardiac disease (e.g. congestive heart failure, symptomatic coronary artery disease and cardiac dysrhythmia, e.g. atrial fibrillation, even if controlled with medication) or myocardial infarction within the past 12 months.

Sponsor

Not provided