Effect of Mulberry Leaf Extract Capsule on Blood Glucose Control in Healthy Volunteers
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 56
- 主要终点
- Blood glucose
研究概览
简要总结
Volunteers will be divided into 4 groups which are mulberry leaf extract 6 mg capsule, mulberry leaf extract 12 mg capsule, mulberry leaf extract 18 mg capsule, and placebo capsule group. They will be tested blood glucose levels (taken from the fingertips) before starting. Then, they will take 1 capsule of the sample one time. After taking the sample for 30 minutes, they will take 50 g of sucrose in 250 ml of water in 5 minutes. Then, they will be tested blood glucose levels (taken from the fingertips) at 30, 60, 90, and 120 minutes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 18-60 years
- •No diabetes mellitus
- •Have blood glucose less than 126 mg/dL
- •Wiling to attend the study
排除标准
- •Take steroids, psychiatric medicine, thiazide diuretic medicine, and beta blocker medicine within 2 weeks before starting of the study
- •Take dietary supplement, herbal substance, and weight-loss medicine within 2 weeks before starting of the study
- •Uncontrolled diseases
- •History of gastrointestinal tract surgery
- •Liver and Kidney diseases
- •Pregnancy and lactation
研究组 & 干预措施
Mulberry leaf extract 6 mg capsule
Take one capsule of the sample one time.
干预措施: Mulberry leaf extract 6 mg capsule (Drug)
Mulberry leaf extract 12 mg capsule
Take one capsule of the sample one time.
干预措施: Mulberry leaf extract 12 mg capsule (Drug)
Mulberry leaf extract 18 mg capsule
Take one capsule of the sample one time.
干预措施: Mulberry leaf extract 18 mg capsule (Drug)
Placebo capsule
Take one capsule of the sample one time.
干预措施: Placebo capsule (Drug)
结局指标
主要结局
Blood glucose
时间窗: 120 minutes
Volunteers will be measured the blood glucose using blood glucose meter and strip (accuchek) before and after taking the sample for 30, 60, 90, and 120 minutes.
次要结局
未报告次要终点
研究者
Pornanong Aramwit, Pharm.D., Ph.D
Professor
Chulalongkorn University