respiratory depression effect of dexmedetomidine for sedation in total knee replacement
Not Applicable
- Conditions
- Not Applicable
- Registration Number
- KCT0005749
- Lead Sponsor
- The Catholic University of Korea, Daejeon St. Mary's Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 82
Inclusion Criteria
American society of anesthesiology (ASA) physical status 1, 2, 3
Age: 50-80 yrs
Patients for total knee replacement surgery under spinal anesthesia
Exclusion Criteria
Severe bradycardia, HR <50 ?/min
Severe cardiopulmonary disease, ASA 4??
Severe hepatic or renal disease
Body mass index > 35
contraindication to spinal anesthesia
Allergy to study medicine, propofol, dexmedetomidine
History of severe obstructive sleep apnea or a tendency for airway obstruction
Refusal of intraoperative sedation
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Respiratory compilcation (respiratory depression, airway obstruction)
- Secondary Outcome Measures
Name Time Method postioperative pain