The Minnesota Manual Dexterity Test As A Measure Of Hand Function in Multiple Sclerosis

Completed

• Conditions: Multiple Sclerosis

• Registration Number: NCT04721340
• Lead Sponsor: Istanbul Aydın University

Brief Summary

The aim of the study is to report the results of manual dexterity using the Minnesota Manual Dexterity Test in people with Multiple Sclerosis.

Detailed Description

Upper limb can be affected even in early stage in people with Multiple Sclerosis (pwMS). Manual dexterity is important to maintain upper limb function and 9-Hole Peg Test (9HPT) is used as gold standard to assess dexterity in pwMS. There are no studies evaluating manual dexterity with the Minnesota Manual Dexterity Test (MMDT) in pwMS. This study aims to:

1. reporting the results of manual dexterity using the Minnesota Manual Dexterity Test and comparing the test results with healthy volunteers,

2. examining the relationship between MMDT and 9HPT, ABILHAND, grip strength, pinch strength, fatigue.

Study Timeline

• Study First Submitted: 2021-01-19
• Study First Submitted QC: 2021-01-21
• Study First Posted: 2021-01-22
• Study Start: 2021-02-02
• Primary Completion: 2021-05-02
• Study Completion: 2021-05-16
• Status Verified: 2021-06
• Last Update Submitted: 2021-06-14
• Last Update Posted: 2021-06-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• (1) age 18-65;
• (2) definitive diagnosis of MS according to McDonald criteria;
• (3) ability to read and write in Turkish.

Exclusion Criteria

• (1) acute attacks of MS (within 3 months);
• (2) cognitive impairment (Mini Mental test result 24 points and below);
• (3) having spasticity (3 and above according to Modified Ashworth Scale)
• (4) any chronic disease other than MS;
• (5) being addicted to alcohol or drugs,

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Minnesota Manual Dexterity Test	baseline (on the predetermined assessment day)	to assess manual dexterity, higher scores mean a worse outcome.

Secondary Outcome Measures

Name	Time	Method
9-Hole Peg Test	baseline (on the predetermined assessment day)	to assess manual dexterity. higher scores mean a worse outcome.
ABILHAND	baseline (on the predetermined assessment day)	to assess for performance of activity. score range 0-46 point, higher scores mean a better outcome.
Fatigue Severity Scale	baseline (on the predetermined assessment day)	to assess fatigue. score range 0-7 point, higher scores mean a worse outcome.
grip strength	baseline (on the predetermined assessment day)	using hand dynamometer. higher scores mean a better outcome.
pinch strength	baseline (on the predetermined assessment day)	using pinchmeter. higher scores mean a better outcome.

Trial Locations

Locations (1)

Istanbul Aydin University; 🇹🇷 Istanbul, Küçükçekmece, Turkey