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Clinical Trials/NCT04933110
NCT04933110
Unknown
Not Applicable

Investigation of Hand Functions and Related Parameters in People With Multiple Sclerosis in the Very Early Stage.

Uğur OVACIK0 sites90 target enrollmentJuly 5, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Multiple Sclerosis
Sponsor
Uğur OVACIK
Enrollment
90
Primary Endpoint
Motor Activity Log-28
Last Updated
4 years ago

Overview

Brief Summary

The upper extremity in people with Multiple Sclerosis (pwMS) has become a more popular research topic in recent years, with the increase in studies reporting widespread involvement. The aim of our study was to evaluate the upper extremity from multiple perspectives in early stage pwMS, to identify problems by comparing them with healthy individuals, and to examine the relationship of problems with activity and participation.

Registry
clinicaltrials.gov
Start Date
July 5, 2021
End Date
September 20, 2021
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Uğur OVACIK
Responsible Party
Sponsor Investigator
Principal Investigator

Uğur OVACIK

Principal Investigator, PT, Msc

Istanbul Aydın University

Eligibility Criteria

Inclusion Criteria

  • MS diagnosis according to McDonald criteria
  • Relapsing Remitting MS clinical course type
  • 18-65 age range
  • Being able to understand and read Turkish

Exclusion Criteria

  • Having an MS attack in the last 3 months
  • To have done regular exercise for the upper extremity in the 6 months before starting the study
  • Having different neurological, orthopedic or cardiac problems other than MS
  • Being addicted to alcohol or drugs
  • Getting a score below 24 on the Mini Mental Test Scale
  • Having a spasticity of 3 or more according to the Modified Ashworth Scale

Outcomes

Primary Outcomes

Motor Activity Log-28

Time Frame: baseline (on the predetermined assessment day)

To assess for performance of activity. Score range 0-5 point, a high score indicates good upper extremity use frequency and quality of movement during activity.

Community Integration Questionnaire

Time Frame: baseline (on the predetermined assessment day)

To assess participation. The total score ranges from 0-29, and the higher the score, the higher the individual's participation in society is considered.

Minnesota Manual Dexterity Test

Time Frame: baseline (on the predetermined assessment day)

To assess upper extremity function. Completing the test in a short time (seconds) indicates better upper extremity function.

ABILHAND

Time Frame: baseline (on the predetermined assessment day)

To assess for performance of activity. Score range 0-46 point, higher scores mean a better outcome.

Nine Hole Peg Test

Time Frame: baseline (on the predetermined assessment day)

To assess upper extremity function. Completing the test in a short time (seconds) indicates better upper extremity function.

Secondary Outcomes

  • Pinchmeter(baseline (on the predetermined assessment day))
  • Symbol Digit Modalities Test(baseline (on the predetermined assessment day))
  • Fatigue Severity Scale(baseline (on the predetermined assessment day))
  • Hand Held Dynamometer(baseline (on the predetermined assessment day))
  • Hand Dynamometer(baseline (on the predetermined assessment day))
  • Tuning fork(baseline (on the predetermined assessment day))
  • Hospital Anxiety and Depression Scale(baseline (on the predetermined assessment day))
  • Aesthesiometer(baseline (on the predetermined assessment day))

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