IRCT2016122722134N4
Completed
Phase 2
Comparison in myocardial perfusion between the intracoronary versus intralesional eptifibatide administration during primary percutaneous coronary intervention in acute ST-segment elevation myocardial infarction; A randomized clinical trial
Vice Chancellor for research of Isfahan University of Medical Sciences0 sites60 target enrollmentTBD
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- cardiovascular disease.
- Sponsor
- Vice Chancellor for research of Isfahan University of Medical Sciences
- Enrollment
- 60
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Diagnosis of ST elevation myocardial infarction (STEMI) as defined by chest pain suggestive for myocardial ischemia for at least 30 minutes before hospital admission and symptoms onset time was less than 12 hours with 1 mm ST segment elevation in 2 or more contiguous leads (for V1\-V3 ST elevation was 2 mm) simultaneously; These patients should also have three or more thrombus burden grade on the angiography. Thrombus burden was graded (G) as G0 \= no thrombus, G1 \= possible thrombus, G2 \= small (greatest dimension \= 1/2 vessel diameter), G3 \= moderate (\> 1/2 but \< 2 vessel diameter), G4 \= large (\= 2 vessel diameter), G5 \= unable to assess TB due to vessel occlusion; undergoing PCI; The consent of patients or their families to participate in the study; insensitivity to Eptifibatide
- •Exclusion criteria: Rescue PCI after thrombolytic therapy; Contraindications for antiplatelet such as bleeding disorder including gastrointestinal bleeding, hematuria, or known any bleeding tendency; thrombocytopenia (Platelet count\<100\.000/cm3\); recent stroke (less than 6 months) and cardiogenic shock
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Not specified
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