Dutch Antibiotics in RSV infection Trial.
Completed
- Conditions
- RSV lower respiratory tract disease (bronchiolitis or pneumonia).
- Registration Number
- NL-OMON22490
- Lead Sponsor
- VU university medical centerDr. M.C.J. Kneyber, paediatricianOffice 8 D 11P.O. Box 70571007 MB AmsterdamThe NetherlandsPhone: 003120-4442413Fax: 003120-4443045e-mail: m.kneyber@vumc.nl
- Brief Summary
Pediatr Pulmonol. 2008 Feb;43(2):142-9.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
Children <24 months of age with a virologically confirmed diagnosis of RSV lower respiratory tract disease, defined by a first episode of dyspnoea with increased body temperature (> 37.5° C), and/or cough, and/or coryza, and/or wheezing, and/or crackles on pulmonary auscultation.
Exclusion Criteria
Age >24 months, children presenting with apnoea with signs of lower respiratory tract disease, nosocomial RSV infection, antibiotic treatment less than 7 days before hospital admission, abscence of informed consent by parents or legal representatives.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of hospitalisation.
- Secondary Outcome Measures
Name Time Method 1. Proportion and duration of oxygen therapy;<br><br />2. Proportion and duration of bronchodilator therapy;<br><br />3. Duration of tachypnoe (>40 breaths/min);<br><br />4. Duration of fever (> 37.5°C);<br><br />5. Duration of impaired feeding;<br><br />6. Number of infants referred to PICU<br>Course of RSV score.