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Clinical Trials/NCT03791749
NCT03791749
Completed
Not Applicable

A Randomised Controlled Trial Testing the Use of a Simple Intervention on Maternal Psychological State, Breast Milk Composition and Volume, and Infant Behaviour and Growth.

University College, London1 site in 1 country72 target enrollmentJanuary 25, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Breastfeeding
Sponsor
University College, London
Enrollment
72
Locations
1
Primary Endpoint
Maternal stress change at 6 weeks from 2 weeks post-delivery.
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Breastfeeding has various benefits for the mother and infant. It has the capability of reducing the risk of short term and long term problems for the infant, such as gastroenteritis, respiratory infections, type II diabetes and obesity, and of providing benefits for neurodevelopment. Breast milk offers even greater benefits for preterm infants. Some of the advantages of breastfeeding are related to the constituents of breast milk such as the macronutrients and bioactive factors, the hormones associated with breastfeeding such as oxytocin, and the behavioural aspects of breastfeeding (maternal sensitivity to infant cues). Despite these advantages, breastfeeding rates are below target levels mainly due to the challenges that women face that hinder breastfeeding success. Interventions aimed at improving policies, practices, and maternal support have been developed. However, other interventions that target specific modifiable barriers to breastfeeding can be useful.

The aim of this study is to investigate a simple support intervention for breastfeeding mothers of late preterm and early term infants on maternal stress reduction and infant weight gain. The investigators also aim to study the potential mechanisms by which this effect could be achieved (breast milk composition and volume, mother and infant behaviour).

Registry
clinicaltrials.gov
Start Date
January 25, 2019
End Date
March 13, 2021
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Mothers of late preterm infants (34 to \<37 weeks) or early term infants (37 to 38 weeks)
  • Intending to breastfeed for at least 6 weeks
  • Free from serious illness
  • Fluent in English

Exclusion Criteria

  • Currently smoking or intending to smoke while breastfeeding
  • Not based in London
  • Prior breast surgery

Outcomes

Primary Outcomes

Maternal stress change at 6 weeks from 2 weeks post-delivery.

Time Frame: Home visit 1 (2 weeks postnatally) and Home visit 2 (6 weeks postnatally)

Stress will be measured using the Perceived Stress Scale (0 to 40 points), where higher scores indicate a higher level of perceived stress.

Infant weight change at 6 weeks from 2 weeks post-delivery.

Time Frame: Home visit 1 (2 weeks postnatally) and Home visit 2 (6 weeks postnatally)

Infant weight (kg) will be measured using an infant weighing scale.

Secondary Outcomes

  • Infant behaviour change at 6 weeks from 2 weeks post-delivery.(Home visit 1 (2 weeks postnatally) and Home visit 2 (6 weeks postnatally))
  • Breast milk hormones change at 6 weeks from 2 weeks post-delivery.(Home visit 1 (2 weeks postnatally) and Home visit 2 (6 weeks postnatally))
  • Mother-infant attachment change at 6 weeks from 2 weeks post-delivery.(Home visit 1 (2 weeks postnatally) and Home visit 2 (6 weeks postnatally))
  • Breast milk composition (macronutrients) change at 6 weeks from 2 weeks post-delivery.(Home visit 1 (2 weeks postnatally) and Home visit 2 (6 weeks postnatally))
  • Breast milk volume change at 6 weeks from 2 weeks post-delivery.(Home visit 1 (2 weeks postnatally) and Home visit 2 (6 weeks postnatally))
  • Infant appetite change at 6 weeks from 2 weeks post-delivery.(Home visit 1 (2 weeks postnatally) and Home visit 2 (6 weeks postnatally))
  • Exclusive Breastfeeding Status(6 weeks, 3 months and 6 months postnatally)

Study Sites (1)

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