Effect of Furosemide on Confirmation of Ureteral Patency During Routine Cystoscopy
- Registration Number
- NCT02960412
- Lead Sponsor
- University of South Florida
- Brief Summary
This study evaluates if administration of IV furosemide leads to expedited confirmation of ureteral patency when compared to placebo (IV saline) in routine cystoscopy performed after urogynecologic surgery.
- Detailed Description
Cystoscopy is performed routinely after urogynecologic surgery to ensure there was no injury to the urinary tract (urethra, bladder, or ureters). In order to confirm that no damage occurred to the ureters, a jet of urine must be visualized from each ureteral opening.
The time it takes to confirm this ureteral patency is variable and some sources suggest using furosemide to decrease the time it takes to see these jets. This study will evaluate what effect, if any, this medicine has on time to confirming ureteral patency.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 150
- Undergoing any urogynecologic surgery
- No allergy or contraindication to receiving furosemide
- Normal Creatinine/glomerular filtration rate
- Unable to consent, including if non English speaking
- Allergy or contraindication to receiving furosemide
- Intraoperative injury to the lower urinary tract
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description placebo Normal Saline normal saline 1mL IV push for one dose furosemide furosemide furosemide 10mg (1mL) IV push for one dose
- Primary Outcome Measures
Name Time Method time to ureteral patency intra-operative time to confirmation of ureteral patency in seconds
- Secondary Outcome Measures
Name Time Method adverse effects from furosemide administration immediately post operative (1-3 days post operatively)
Trial Locations
- Locations (1)
Tampa General Hospital
🇺🇸Tampa, Florida, United States