Cost-effectiveness of interpretation bias modification in patients with major depressive disorder: a randomised controlled trial.

Completed

• Conditions: Major Depressive Disorder; Depression; 10027946

• Registration Number: NL-OMON47198
• Lead Sponsor: Trimbos-instituut

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 196

Inclusion Criteria

- A diagnosis of major depressive disorder, first or recurrent, as assessed with the MINI (which makes use of DSM-IV-TR criteria).
- 18-65 years old.
- Waitlisted for treatment for depressive disorder or having received no more than 4 indicated psychotherapy sessions.
- Provides informed consent

Exclusion Criteria

-Any psychotic disorder (current or previous)
-Current mania or hypomania or a history of bipolar disorder
-Cognitive disabilities (IQ < 80)
-Visual disabilities that interfere with a computer task
-Acute suicidal risk
-No sufficient command of Dutch language to participate in the study
-Lack of sufficient experience with the use of computers (based on subjective estimation of the patient)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Clinical evaluation: The main outcome is the change in depressive symptoms as<br /><br>measured by the Beck depression Inventory.<br /><br>Economic evaluation: The EQ-5D will be used to assess QALY*s and costs will be<br /><br>assessed with the TiC-P.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Interpretation biases, prospective and every day use of imagery, dysfunctional<br /><br>cognitions, levels of anxiety, diagnostic status, treatment expectancies and<br /><br>satisfaction with treatment. </p><br>