Whole-Body MRA at 3T - A Comparison Between Two Different Scan Protocols
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 26
- 试验地点
- 1
- 主要终点
- Diagnostic quality of WB-MRA
研究概览
简要总结
To compare to different approaches in whole-body magnetic resonance angiography of patients suffering peripheral arterial disease.
Our hypothesis is that use of a new protocol improves the diagnostic quality of the WB-MRA procedure.
详细描述
Patients suffering peripheral arterial disease must undergo imaging procedures before endovascular or surgical procedures.
WB-MRA is an imaging procedure that can visualise the arterial system. WB-MRA can be performed in different manners. On option is to start the scan in the head region and continue down the body to the feet (standard protocol). Another option is to use a hybrid protocol that first examines the head and lower leg followed by examination of the pelvic and upper leg region.
A comparison between the standard and hybrid protocols has not been performed in a 3T high magnetic field system, therefore we will perform such a study.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Symptomatic lower extremity ischemia (claudication, ischemic wounds)
- •Referred to digital subtraction angiography (DSA)
排除标准
- •Renal insufficiency (GFR < 30 ml/min)
- •Contra-indications for MRI-examination (claustrophobia, metal-implants, pacemaker)
- •Pregnancy/lactation
- •Allergy to gadolinium based MRI contrast agents
- •Acute disease
结局指标
主要结局
Diagnostic quality of WB-MRA
次要结局
- Signal to noise ratio
- Contrast to noise ratio