Whole Body Magnetic Resonance Angiography in Patients With Symptomatic Peripheral Ischemia. Experience With Venous Compression.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Vascular diagnostic quality on the WB-MRA. Degree of arterial stenosis on the WB-MRA
研究概览
简要总结
To investigate the diagnostic performance of whole body magnetic resonance angiography (WB-MRA) using subsystolic venous compression of the thigh.
详细描述
WB-MRA is an examination that can evaluate the arteries from head to feet. Timing of the injected bolus of contrast medium can be difficult, especially in the legs. As the result of the WB-MRA depends on the contrast medium only being in the arteries at the time of examination, the use of venous compression is a possible way of overcoming the problem of early venous filling, that can hamper the diagnostic value of the examination. Venous compression is performed with a blod pressure cuff around the thighs. It is inflated to subsystolic pressure (45 mm Hg). This elevated pressure leads to filling of the lower leg arteries and late venous filling.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Symptomatic lower extremity ischemia (claudication, ischemic wounds)
- •Referred to digital subtraction angiography (DSA)
排除标准
- •Renal insufficiency (GFR < 30 ml/min)
- •Contra-indications for MRI-examination (claustrophobia, metal-implants, pacemaker)
- •Pregnancy/lactation
- •Allergy to gadolinium based MRI contrast agents
- •Acute disease
结局指标
主要结局
Vascular diagnostic quality on the WB-MRA. Degree of arterial stenosis on the WB-MRA
时间窗: 1 month
次要结局
未报告次要终点