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Clinical Trials/NCT06669455
NCT06669455
Recruiting
Not Applicable

SENSS (Stress, Exercise, Nutrition, Sleep, Self-management): an Integrated, Personalized and Stepped Care Lifestyle Approach for People with Parkinson's Disease: a Randomized Controlled Trial

Radboud University Medical Center1 site in 1 country256 target enrollmentNovember 12, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Parkinson Disease
Sponsor
Radboud University Medical Center
Enrollment
256
Locations
1
Primary Endpoint
Change in quality of life measured with the PDQ-39.
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

The goal of this study is to investigate the effects of a combined lifestyle program on the quality of life in people with Parkinson's Disease.

Participants will be randomly assigned to one of two groups, both receiving standard care, a Parkinson Lifestyle Decision aid and an intake meeting with a lifestyle coach. One group will work on their goals independently, while the other group will get guidance from the lifestyle coach throughout the 12-month program. The program focuses on self-management, exercise, nutrition, sleep and stress.

Participants will complete questionnaires after 0, 6 and 12 months, and use a wearable sensor for two weeks. The main outcome is quality of life over 12 months, measured with the PDQ-39 questionnaire. The study also examines personal goal achievements, symptom changes, and the economic effects of the program.

Registry
clinicaltrials.gov
Start Date
November 12, 2024
End Date
December 2026
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Parkinson's disease (idiopathic) in all stages of severity
  • Proficient in Dutch, for both the data collection (questionnaires) and the intervention (all of the apps/modules are in Dutch)
  • Aged 18 or older

Exclusion Criteria

  • Cognitive impairments that do not allow to fill out the questionnaires, as judged by the researcher during the screening call.
  • Not in possession of or no access to an electronic device that allows for (video) calls with a lifestyle coach, and to complete questionnaires.
  • Planned surgery or a planned major change in healthcare provision.

Outcomes

Primary Outcomes

Change in quality of life measured with the PDQ-39.

Time Frame: Measured at baseline, and after 6 and 12 months.

The PDQ-39 consists of 39 questions across 8 dimensions of daily living including relationships, social situations and communication. Item scores range on a 5-point scale from "never" to "always". Both the total score of the PDQ-39 and the scores for each of the 8 dimensions are considered primary outcomes.

Secondary Outcomes

  • Health related quality of life(Measured at baseline, and after 6 and 12 months.)
  • Parkinson's Disease Symptoms(Measured at baseline, and after 6 and 12 months.)
  • Fatigue(Measured at baseline, and after 6 and 12 months.)
  • Goal Attainment(Measured at baseline, and after 6 and 12 months.)
  • Diet quality(Measured at baseline, and after 6 and 12 months.)
  • Mood (Anxiety and Depression)(Measured at baseline, and after 6 and 12 months.)
  • Physical activity level(Measured at baseline, and after 6 and 12 months.)
  • Insomnia(Measured at baseline, and after 6 and 12 months.)
  • Sleepiness(Measured at baseline, and after 6 and 12 months.)
  • Self-Efficacy(Measured at baseline, and after 6 and 12 months.)
  • Ilness Acceptance(Measured at baseline, and after 6 and 12 months.)
  • Coping(At baseline.)
  • Self-management(Measured at baseline, and after 6 and 12 months.)
  • Change in physical activity from baseline to 12 months(Measured one week at baseline and one week after 12 months.)
  • Change in sleep time from baseline to 12 months(Measured one week at baseline and one week after 12 months.)
  • Change in sleep quality from baseline to 12 months(Measured one week at baseline and one week after 12 months.)

Study Sites (1)

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