Low-Volume Interval Training and Resistance Exercise in Individual With Stroke
- Conditions
- Stroke
- Interventions
- Other: Combination of Low-volume interval treadmill training and Resistance Training
- Registration Number
- NCT04623060
- Lead Sponsor
- Universiti Teknologi Mara
- Brief Summary
To examine the feasibility of Low-Volume Interval Training (LV-ITT) and Resistance Exercise (RE) on walking performance (walking endurance, gait speed, functional balance), lower limb muscle strength and quality of life among individuals with post-stroke.
- Detailed Description
Prescribing aerobic and resistance training in concurrence is proposed as an optimum strategy to target cardiovascular as well as musculoskeletal functions in individuals with post-stroke. Lower limb's resistance training alone in chronic stroke produces a large effect on muscle strength. However, it has shown uncertainty results on walking performance. Therefore, it is suggested that to prescribe mix training (treadmill training and strength training) in order to improve muscle strength, gait performance and quality of life in stroke survivors. Previous studies have shown the effect of mixed training on walking performance and endurance in other populations such as multiple sclerosis and coronary artery disease. However, there is a lack of study that conducted mixed training among chronic post-stroke. Therefore, the feasibility study on the effectiveness of combining LV-ITT and RE in post-stroke should be conducted.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 30
- Age range between 45-65 years' old
- At least 3-months post-stroke
- Gait speed ≤1.0 m·s -¹ measured by the 10 m walk test.
- Able to walk 10 m overground with assistive devices as needed and no physical assistance.
- Able to walk for 3 min on the treadmill at ≥0.17 m·s -¹ (0.4 mph) with no aerobic exercise contraindications.
- Modified Rankin Score (mRS) of <4 at the screening
- American Heart Association class B (2), allowing for aerobic capacity <6 metabolic equivalent (MET)
- Significant resting ECG abnormalities
- Hospitalization for cardiac or pulmonary disease within 3 months
- Using Pacemaker
- Aphasia
- Significant musculotendinous or bony restrictions of the affected limb, or any serious chronic disease independently causing disability or profound atrophy of the affected limb that will comprise further indications to participation significant.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Intervention Combination of Low-volume interval treadmill training and Resistance Training 3 sessions/week for 6 weeks
- Primary Outcome Measures
Name Time Method Change in Six Minute Walk Test 0, 6 weeks This test measures the distance that an individual can quickly walk in a period of 6 minutes on a flat surface. Participants will complete one trial with the gait aide prescribed to them. The distance will be recorded. Participants can stop and rest or discontinue to the test at any time.
- Secondary Outcome Measures
Name Time Method Change in Timed Up and Go test 0, 6 weeks Functional Balance
Patient satisfaction 6 weeks Questionnaire
Change in 10-meter walk test 0, 6 weeks This assessment will include four 10-meter walking tasks at maximal comfortable speed.
Change in Lower Limb Muscle Strength 0, 6 weeks Handheld dynamometer for knee extensor
Adherence 0 to 6 weeks Attendance and completion of home-based sessions measured via exercise diary
Stroke Impact Scale (SIS) 0,week 6 Quality of Life
Adverse Events 0 to 6 weeks Any adverse event or near miss is required to be reported as standard of care at Selayang Hospital
Trial Locations
- Locations (1)
Hospital Selayang
🇲🇾Batu Caves, Selangor, Malaysia