Phase II study of neoadjuvant chemotherapy TS-1/CPT-11 for advanced lower rectal cancers
Not Applicable
- Conditions
- Rectal cancers
- Registration Number
- JPRN-UMIN000000962
- Lead Sponsor
- Dept. Surgery Kyoto University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
Not provided
Exclusion Criteria
Excluded are cases with conditions as below: 1) Multiple malignancies to be treated. 2) Previous history of severe drug-induced allergy. 3) Active infectious diseases. 4) Coexistent severe diseases including pulmonary fibrosis, interstitial pneumonia, ileus, uncontrollable diabetes, cardiac dysfunction, hepatic failure, or renal failure. 5) Peritoneal or pleural fluid retention to be drainaged. 6) Symptomatic brain metastases. 7) Active digestive tract bleeding. 8) Severe watery diarrhea. 9) Pregnant. 10) Previous treatment history of radiotherapy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 3-year disease-free survival rates
- Secondary Outcome Measures
Name Time Method