NCT07593547招募中不适用
Combination vs. Monotherapy for Stenotrophomonas Maltophilia Infections: A Multicentre Study Using Target Trial Emulation
Instituto de Investigación Sanitaria Gregorio Marañón1 个研究点 分布在 1 个国家目标入组 790 人开始时间: 2026年3月6日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 790
- 试验地点
- 1
研究概览
简要总结
The goal of this multicentre observational study is to analyse the treatment strategies and the outcomes for patients with S. maltophilia infections using target trial emulation methodology. The main question it aims to answer is:
• Does combined therapy achieve better results than monotherapy in treating S. maltophilia infections?
Researchers will compare groups receiving monotherapy and combined therapy to see if there are differences in all-cause 30-day mortality.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients
- •S. maltophilia infections
- •Different episodes if a new infection ocurred > 30 days since the index episode
排除标准
- •isolates obtained from patients outside of hospital admission
- •microbiological or clinical colonization
- •hospitalizations shorter than 72 hours since the time zero
- •patients who died in the first 72 hours since the time zero or who were in imminent risk of death
- •polymicrobial infections
- •receipt of inappropriate therapy after the time of the emulated randomization, defined as the absence of in vitro active antimicrobials or the administration of active antimicrobials for less than 48 hours
- •absence of data outcomes
研究者
Sofia De La Villa
MD
Instituto de Investigación Sanitaria Gregorio Marañón
研究点 (1)
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