Effects of Breathing and Attention Training (BAT) on Pain Modulation
- Conditions
- Fibromyalgia
- Registration Number
- NCT05773482
- Lead Sponsor
- University of Florida
- Brief Summary
The hypersensitivity of fibromyalgia is associated with abnormal pain modulation within the CNS, but not with peripheral or central sensitization. Many brain areas that contribute to modulation of pain are known, but their testing is complex and expensive. Quantitative sensory testing is easier to perform and repeatable. Therefore, it will be used to evaluate the effects of Breathing Attention Training (BAT) on the hypersensitivity of FM participants. BAT is a form of mindfulness meditation shown to decrease FM symptoms and possibly pain sensitivity. We hypothesize that pain modulation of chronic pain patients is improved by BAT.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 40
- Individuals diagnosed with fibromyalgia will have pain of duration > 6 months and meeting the 1990 Research Diagnostic Criteria for FM (ACR)
- Healthy, pain-free age matched controls without chronic pain
- Personal or family history of photosensitive epilepsy
- Prior history of cancer or diabetes
- Patients must be willing to discontinue their analgesics, hypnotics, anxiolytics, or anti-depressants during the study period for at least 5 half-lives.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Ratings of Painful and Painless Sensory Stimuli 2 hr Ratings of painful and non-painful stimuli in FM subjects and HC will be obtained before and after BAT or Deep Breathing. Painful stimuli will include pressure stimuli. Painless stimuli will consist of flashing light stimuli.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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Trial Locations
- Locations (1)
University of Florida
🇺🇸Gainesville, Florida, United States
University of Florida🇺🇸Gainesville, Florida, United StatesMelyssa GodfreyContact352-265-8901Melyssa.Godfrey@medicine.ufl.eduRoland Staud, MDPrincipal Investigator