Efficacy of castor oil in the management of Rheumatoid arthritis.

Phase 4

Completed

Conditions: The Patients of disease Amavata having classical Sign and symptoms of Sama stage will be selected for the Study

Registration Number: CTRI/2016/12/007569

Lead Sponsor: Institute for Post Graduate Teaching and Research in Ayurveda Gujarat Ayurved University Jamnagar

Brief Summary: In 21st century Rheumatoid arthritis (RA) has been more common& distressing among all joints problem. About 1% of world population is affected by RA.Females are three times more affected than male. It is a chronic inflammatory joint disease with multi system involvement. Even in modern medical science with extreme advancement in diagnostic approach, only symptomatic relief and no permanent cure can be given. Hence for Ayurvedic scholar it is a challenging disease, so it becomes duty of scholars to work on various aspect of this disease. Rheumatoid Arthritis can be correlated with disease Amavata mentioned in Ayurvedic text book.All symptoms mention are characteristic of *Ama* & without treating *Ama* it is not possible to treat the disease so in this condition drug having *Ushna*, *Tikshna*, *Deepan*, *Pachan*, *Vatashamak*, *Shothhara* Properties can be used, when *Ama* is digested then drug having *Vatashamak* properties remain useful, only after digestion of *Ama* other drugs can be used. The property of *Ama* is *Guru*, *Snigdha*, *Sheet*, *Pichchhil* and *Manda*. In Ayurvedic classics *Erand* *Sneha* has been mentioned as drug of choice for the disease *Amavata*due to having its *Katu*, *Tikshna*, *Ushna* properties, *Shunthi* increase digestive fire, make interest toward food and pacify *Vata* and *Kapha* *shamak* properties.After completion of therapy it is found that in *Sama* condition (Acute stage) of disease Amavata (Rheumatoid arthritis) both Erand Sneh and Shunthi Kwath was found effective and provide better relief in subjective and objective parameters. Group A (Erand Sneh and Shunthi Kwath) was found more effective than group B ( only Erand Sneh)

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 60

Inclusion Criteria

Patients fulfilling the diagnostic criteria especially having symptoms of sama stage of disease Willing & able to participate in the study.

Exclusion Criteria

1.Less than 20 & more than 60 years 2.Patients having symptoms of RA but having absence of Sama symptoms.
3.Patients with complication of RA e.g. Pleuro-Pericardial disease, cardiac disease etc.
4.Patients with poorly controlled HTN, DM etc.
5.Patients on prolong medication especially corticosteroids, anticholinergics etc.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
RELIEF OF Symptoms of Sama stage of disease AMAVATA i.e. pichhil mala tyaga , Ashradhdha, Aruchi, Angagaurav, Jwara, Asya Samsravana, Asya Pichchhilatva, Hrillasa etc. symptoms of RA (As mentioned according to revised criteria of American association of rheumatology 1987 ) with stiffness of affected joints , severe tenderness ,swelling of affected joints , redness (sero-positive or sero-negative)	18 Months

Secondary Outcome Measures

Name	Time	Method
symptoms of RA (As mentioned according to revised criteria of American association of rheumatology 1987 ) with stiffness of affected joints , severe tenderness ,swelling of affected joints , redness .	UPTO PRESENT STUDY

Trial Locations

Locations (1): OPD Building OPD No 26
🇮🇳
Jamnagar, GUJARAT, India
OPD Building OPD No 26
🇮🇳Jamnagar, GUJARAT, India
Dr Darshna Pandya
Principal investigator
9099011095
darshnapandya@rediffmail.com