CT-angiographic Follow Upp of Patients That Underwent Coronary Bypass Surgery Between 1993-1997. A Randomized Longitudinal Trial.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 52
- 试验地点
- 2
- 主要终点
- Patency of the grafts
研究概览
简要总结
Coronary artery surgery (CABG) is necessary to improve blood circulation in many patients with coronary artery disease. This is done by using alternative blood vessels (grafts) to bypass the stenosed coronary arteries. In CABG, vein grafts are traditionally used where surrounding tissue is removed, this may damage the vessel and influence its patency.
The "no-touch" technique was developed by Professor Domingos Souza at the Department of Cardiovascular and Thoracic Surgery, Örebro University Hospital. This technique includes taking out the vein with its surrounding tissue and by this way the vessel is less damaged. The first two follow ups have shown that no-touch grafts had better patency than conventionally extracted graft at 18 months and 8.5 years.
This long term follow up is a continuation of the randomized trial started in 1993 where the patency and incidence of stenoses in the no touch and conventional vein grafts has been studied.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •First time coronary artery bypass grafting with either conventional or no touch vein grafts performed by Dr.Souza between 1993-
- •Included in the previous follow up studies
- •Signed and dated consent.
排除标准
- •Allergy to contrast
- •Renal failure
- •Uncontrolled diabetes
- •Unable to implement the study according to protocol -
结局指标
主要结局
Patency of the grafts
时间窗: Mean time of 15 years.
次要结局
- Stenosis in the grafts.(Mean time of 15 years.)
研究者
Ninos Samano M.D.
Doctor
Örebro County Council