A CLINICAL TRAIL TO STUDY THE ANALGESIC EFFICACY OF ORAL CLONIDINE VS INTRATHECAL CLONIDINE WHEN ADDED AS AN ADJUVANT TO 0.5% HYPERBARIC BUPIVACAINE IN CESAREAN SECTION.
Phase 1
Not yet recruiting
- Conditions
- Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium,
- Registration Number
- CTRI/2021/08/035730
- Lead Sponsor
- Dr Vignesh T M
- Brief Summary
This study is a randomized single centre trial comparing the effect of Intrathecal clonidine vs oral clonidine when added as an adjuvant to 0.5% hyperbaric bupivacaine in patients undergoing cesarean section, that will be conducted in a single centre in india. The primary objective is to measure the duration of analgesia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Female
- Target Recruitment
- 50
Inclusion Criteria
- ASA physical status â… and â…¡.
- Age 18-31 years.
- Singleton pregnancy Informed, written and valid consent.
Exclusion Criteria
- Obstetric complications such as Placenta previa, Abruptio placenta and Preeclampsia.
- Spinal deformity such as kyphoscoliosis.
- BMI greater than 35kg/m2.
- Height less than 150 cm or greater than180 cm.
- Women with Hypertensive disorders,Cardiovascular disorders,Deep vein thrombosis.
- Allergy to study drugs.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the duration of analgesia. Duration of analgesia is assessed every 15 minutes from onset of sensory block to first request for rescue analgesic or VAS score 4 or more.
- Secondary Outcome Measures
Name Time Method Onset and duration of sensory block. Onset and duration of motor block.
Trial Locations
- Locations (1)
Karnataka institute of medical sciences
🇮🇳Dharwad, KARNATAKA, India
Karnataka institute of medical sciences🇮🇳Dharwad, KARNATAKA, IndiaDr Vignesh T MPrincipal investigator9524567167vickyvijay1995@gmail.com