The whole-body cryotherapy in mild cognitive impairment

Not Applicable

Completed

• Conditions: Dementia; Mild Cognitive Impairment; Alternative and Complementary Medicine - Other alternative and complementary medicine; Mental Health - Other mental health disorders; Neurological - Dementias

• Registration Number: ACTRN12619001627145
• Lead Sponsor: Polish Ministry of Science and Higher Education

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2018-12-31
• Study Start: 2019-11-25
• Last Update Posted: 10 December 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

Medically stable (based on physical examination, medical history and vital signs at screening) adults with a diagnosis of mild cognitive impairment (MCI; F06.7 according to research criteria of International Classification of Diseases, ICD-10) (World Health Organization, 2004) with additional inclusion criteria based on the Montreal Cognitive Assessment (MoCA) test (Magierska, Magierski, Fendler, Kloszewska, & Sobów, 2012; Nasreddine et al., 2005; Talarowska, Florkowski, Zboralski, & Galecki, 2011) (scores between 20 and 26).

Exclusion Criteria

The exclusion criteria included 1) a lack of or more advanced cognitive decline (2026), 2) depression, 3) previous exposure to WBC 4) being over 85 years old and 5) all standard contraindications to use WBC (e.g. alcohol and drug abuse, inability to understand questions and written information, psychosis, suicidal thoughts, standard contraindications to use WBC (e.g. acute respiratory diseases, acute cardiovascular disease like coronary disease, circulatory insufficiency, unstable hypertension, cold intolerance, claustrophobia, cryoglobulinemia, cancer, deep vein diseases, hypothyroidism, neuropathies, purulent skin changes, Reynaud disease).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
cognitive functions measured by DemTect® and Saint Louis University Mental Status Examination (SLUMS). [Baseline (T1), after the 10th WBC session (T2) and at follow-up after 2 weeks (T3) with primary timepoint T1 and T2]