Effects of serial whole body cryotherapy on disease activity, functional health, cytokines and marker of bone and cartilage metabolism in rheumatoid diseases, e.g, rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis and primary fibromyalgia, and healthy individuals

Campus Kerckhoff der Justus-Liebig-Universität Gießen0 sites192 target enrollmentApril 8, 2020

Overview

No summary available.

Registry

who.int

Start Date

April 8, 2020

End Date

January 1, 2016

Last Updated

last year

Study Type

Interventional

Sex

All

Sponsor

Campus Kerckhoff der Justus-Liebig-Universität Gießen

•confirmed rheumatoid arthritis according to the ACR/EULAR classification criteria of rheumatoid arthritis of 2010
•\- confirmed psoriatic arthritis according to the CASPAR criteria
•\- confirmed axial spondylarthritis / ankylosing arthritis according to the ASAS classification criteria
•\- confirmed primary fibromyalgia according to the ACR/EULAR criteria of 2010 and the modification of 2011
•\- Health control subjects after medical examination
•\- Written consent and approval of the study
•\- stable medication (antirheumatic as well as analgesic and other basic medication) 4 weeks before starting the study and during the entire study

•Contraindications for whole\-body cold therapy treatment (cryoglobulins, cold urticaria, vasculitis, Raynaud's syndrome, unstable arterial hypertension, peripheral arterial circulatory disorders, cold hypersensitivity, disturbed temperature sensation, bladder and kidney diseases, etc.) .
•No written consent.
•No comprehension of the study.
•Lack of German knowledge.
•Presence of an accompanying secondary pain syndrome in patients with inflammatory rheumatic diseases (RA, PsA, axSpA)