the study is to compare the intubating conditions between succinylcholine, the gold standard drug for rapid sequence induction and rocuronium after treatment with magnesium sulphate which makes the action of rocuronium similar to that of succinylcholine
Not Applicable
- Registration Number
- CTRI/2022/11/046959
- Lead Sponsor
- ABVIMS Dr RML Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA physical status I & II
Body mass index 18.5-24.9 kg/m2
Mallampati grade 1 & 2
surgery under general anaesthesia
Exclusion Criteria
refusal of consent
emergency surgery
anticipated difficult airway
pregnant or breastfeeding patients
patients with hepatic, renal metabolic or neuromuscular disorders
allergic to study drugs
patients receiving drugs that influence neuromuscular functions
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the intubating conditions during rapid sequence intubation using Coopers criteriaTimepoint: intubating conditions will be graded as <br/ ><br>8-9 : excellent <br/ ><br>6-7 :good <br/ ><br>3-5:fair <br/ ><br>0-2:poor
- Secondary Outcome Measures
Name Time Method 1.To study the hemodynamic parameters:heart rate,systolic,diastolic blood pressure amd mean arterial pressure,Sp02 in both groups at following intervals <br/ ><br> <br/ ><br>2.To study the side effects : muscle pain, burning sensation,nausea,vomiting <br/ ><br>Timepoint: baseline (T0) <br/ ><br>before intubation (Ti) <br/ ><br>1 minute after intubation(T1) <br/ ><br>3 minutes after intubation (T3) <br/ ><br>5 minutes after intubation(T5) <br/ ><br>