The value of CT angiography in patients with acute severe headache; a prospective study

Completed

• Conditions: acute severe headache; thunderclap headache; 10007963

• Registration Number: NL-OMON43701
• Lead Sponsor: eurologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 200

Inclusion Criteria

- Acute severe headache, with a maximum within five minute, lasting longer than 1 hour.
- Worst headache ever experienced
- Normal neurological examination
- Normal standard head CT, without lumbar puicture if performed <6 hours of start of headache and evaluated by experienced neuro-radiologist.
- If standard head CT performed >6 hours a lumbar puncture with normal chemistry and opening pressure.

Exclusion Criteria

- Abnormalities on standard head CT; hemorraghe, recent ischaemia, tumor.
- focal abnormalities at neurological examination
- Abnormalities in CSF chemistry of opening pressure, if lumbar puncture is performed.
- Poor of bad kindey function,defined by an eGFR<60ml/min
- Known contrast allergy

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- The number of intracranial abnormalities in this group found by CTA.<br /><br>- All CTA's will be evaluated by experienced neuro-radiologists<br /><br>- The presence of SAH, unruptured aneurysms, cerebral venous thrombosis,<br /><br>carotid or vertrebral arterial dissection and reversible vasocontstriction<br /><br>syndrome will be monitored.<br /><br>- Headache and patient characteristics will be determined in order to apply CTA<br /><br>more purposefully in the future<br /><br>- The number of changed diagnosis due to CTA performance will ben monitored.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>N/A</p><br>