Medication Adherence in Rheumatic Diseases

Not Applicable

Recruiting

• Conditions: Chronic Rheumatic Diseases
• Interventions: Behavioral: Clinician-led adherence intervention

• Registration Number: NCT06018350
• Lead Sponsor: Duke University

Brief Summary

The investigators will pilot test a clinician-led intervention to improve medication adherence in general rheumatology clinic across a spectrum of rheumatic diseases. The study will assess feasibility, acceptability, and fidelity, and explore signal for improved medication adherence.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-08-25
• Study First Submitted QC: 2023-08-25
• Study First Posted: 2023-08-30
• Status Verified: 2023-11
• Study Start: 2024-02-02
• Last Update Submitted: 2024-02-16
• Last Update Posted: 2024-02-20
• Primary Completion: 2024-12
• Study Completion: 2025-06

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• all providers at Southpoint Rheumatology All patients with a rheumatic disease diagnosis currently prescribed at least one rheumatic medication will be included in the analysis

Exclusion Criteria

• new patients, those who are not prescribed any rheumatic disease medications, or do not have available pharmacy refill data

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Intervention	Clinician-led adherence intervention	Clinicians in this arm will be trained to conduct the adherence intervention in general rheumatology clinic with all follow up patients with a chronic rheumatic disease. Patients seen by these clinicians will contribute to the outcome data collection.

Primary Outcome Measures

Name	Time	Method
Intervention Feasibility	4 weeks	Percent of visits with EMR documentation of providers reviewing refills

Secondary Outcome Measures

Name	Time	Method
Change in medication adherence	baseline, 6 months	90-day medication possession ratio at 6 months after the intervention visit compared to baseline
Acceptability	4 weeks	Provider survey based on the Acceptability of Intervention Measure, scores range from 1-5, 5 is most acceptable
Acceptability, as measured by the percentage of patients who report a positive feeling after having an adherence conversation with their providers	4 weeks	Patient survey will be administered after their provider visit
Fidelity	4 weeks	Frequency of EMR documentation of completing the intervention components of reviewing pharmacy refills and using effective communication strategies

Trial Locations

Locations (1)

Duke University; 🇺🇸 Durham, North Carolina, United States