Oxygenation by nose in infants undergoing surgery under general anaesthesia

Not Applicable

• Conditions: Health Condition 1: O- Medical and Surgical

• Registration Number: CTRI/2019/07/020346
• Lead Sponsor: Vijayanagara Institute of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1)Infants of 0 to 6 months age, of either sex, posted for elective / emergency surgeries under general anaesthesia

2)ASA physical status I & II

3)Patients with normal cardiorespiratory function

Exclusion Criteria

1)Refusal by parents for the procedure

2)Infants with fever, upper respiratory tract infection, anaemia(Hb-12gm%), obstructive sleep apnoea(OSA), protein energy malnutrition, overweight(greater then weight for age)

3)Surgeries requiring nasal intubation

4)History of significant systemic disorders, known congenital heart diseases, hypotension (systolic BP <60mmHg) and infants with desaturation before the induction of anaesthesia (SpO2 <94%)

5)Infants with anatomical nasal defects (nasal obstruction) and obvious congenital syndromes

6)Infants with anticipated difficult airway

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Safe apnoea time (fall of SpO2 upto 95%)Timepoint: Baseline readings of SpO2 (before induction), after preoxygenation, after induction, after paralysis, during apnoea, laryngoscopy and intubation noted in seconds

Secondary Outcome Measures

Name	Time	Method
a.Apnoeic times for different levels of desaturation between two groups <br/ ><br>100-99 <br/ ><br>98-97 <br/ ><br>96-95 <br/ ><br>95 <br/ ><br>b. Lowest O2 saturation during study period <br/ ><br>c. Intubation Time <br/ ><br>d. Blood pressure <br/ ><br>e. Heart rate <br/ ><br>Timepoint: Baseline readings of SpO2 (before induction), after preoxygenation, after induction, after paralysis, during apnoea, laryngoscopy and intubation noted in seconds <br/ ><br>Time when SpO2 falls from 100% to 95%