Comparing the effect of two different flow rates of high flow nasal cannula on increasing the oxygen content of blood during the start of general anaesthesia.
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/05/067510
- Lead Sponsor
- Maulana Azad Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA physical status I and II
Exclusion Criteria
Any known contraindication to HFNC: bleeding in nose or oropharynx, pre-existing nasal obstruction, greater than 50 percent of nares occluded by nasal prongs.
Patients on oxygen therapy.
Any underlying chronic or restrictive lung disease (kyphoscoliosis, burn contractures).
Previous lung surgery.
BMI greater than 35 kg per meter square.
Planned for awake intubation or a difficult airway.
Any contra-indication to continuous positive airway pressure (CPAP) treatment.
Pregnant patients, autonomic neuropathy, history of gastro-esophageal reflux disease(GERD).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method PaO2 in both the groups.Timepoint: At the end of 3 minutes of apnoeic oxygenation
- Secondary Outcome Measures
Name Time Method Mean difference in PaO2 and PaCO2 levels in both groups (baseline, after 3 minutes of pre-oxygenation, after 3 minutes of apnoeic oxygenation) . <br/ ><br>End tidal oxygen (FETO2) and End tidal carbon dioxide (ETCO2) after securing a definitive airway and after 3 minutes. <br/ ><br>Percentage of population with hypoxemia (SpO2 less than 92%). <br/ ><br>Patient comfort during pre-oxygenation immediately before induction on a 5 point Likert scale.Timepoint: Baseline, after 3 minutes of pre-oxygenation, after 3 minutes of apnoeic oxygenation, after securing a definitive airway and after 3 minutes of securing a definitive airway.