Cooperative Research Centre (CRC) for Alertness, Safety and Productivity: Respiratory Phenotyping for Obstructive Sleep Apnoea

Not Applicable

Recruiting

• Conditions: Obstructive Sleep Apnoea; Respiratory - Sleep apnoea

• Registration Number: ACTRN12615000069550
• Lead Sponsor: A/Prof Peter Catcheside

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-01-27
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Diagnosed with obstructive sleep apnoea (OSA)
- Recommended usual care with CPAP treatment by their treating physician
- Demonstrated positive treatment response to one night of oxygen therapy (O2 AHI <10 /hr with a =50% reduction compared to the air control night; using modified AHI scoring criteria without SaO2 signal blinding and no desaturation criteria).

Exclusion Criteria

- Smokers (due to risk of fire with home oxygen use)
- Women who are pregnant or who are trying to conceive
- Children and/or young people (i.e. < 18 years)
- Central sleep apnea (central apnea index >5 /hr)
- Any relevant significant co-morbidity including respiratory (COPD) or psychiatric disorders likely to place the patient at higher than normal risk or likely to confound experimental treatment outcomes.
- Physician recommended exclusion
- Patient unable (e.g. language difficulties) or unwilling to consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified