on-invasive CPAP-Ventilation versus Oxygen-therapy using a simple face mask for Carbon Monoxide poisoning

Not Applicable

Completed

• Conditions: Carbon monoxide poisoning; Injury, Occupational Diseases, Poisoning; Accidental poisoning by and exposure to other gases and vapours

• Registration Number: ISRCTN05226190
• Lead Sponsor: Medical University of Vienna

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-06-20
• Study Completion: 2015-07-31
• Last Update Posted: 14 September 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 74

Inclusion Criteria

1. Adult patients (i.e. at least 18 years old) treated at the Emergency Department
2. Elevated levels of COHb (COHb >= 7%) AND either assured CO-exposition (for example, faulty gas-heater, fire) or symptoms consistent with CO poisoning

Exclusion Criteria

1. Patients being comatose on admission
2. Patients intubated by Emergency Medical Service
3. Patients requiring mechanical ventilation
4. Pregnant women

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Absence of neuropsychological sequelae 1 month after intoxication

Secondary Outcome Measures

Name	Time	Method
<br> 1. Time until COHb-level reaches 3% or less<br> 2. Changes in neuropsychological sequelae between hospital discharge and 1 month after intoxication<br> 3. Quality of life after 1 month<br> 4. Mortality after 1 month<br> 5. Adverse events<br> 6. Length of Stay at ICU<br> 7. Length of stay in hospital<br> 8. Hospital admission within 1 month<br>