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Clinical Trials/NCT01341665
NCT01341665CompletedNot Applicable

Subclassification of the Syndrome of Inappropriate Antidiuresis Via Copeptin - What is the Genesis of ADH-independent SIADH?

University of Wuerzburg1 site in 1 country50 target enrollmentStarted: March 2008Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
50
Locations
1
Study OverviewStudy DesignEligibility CriteriaInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

The aim of this study is to evaluate the different types of osmotic dysregulation in patients with Syndrome of Inappropriate ADH (SIADH) and, hence, to analyze the pathophysiology of SIADH.

These types will be characterized by measurement of AVP and copeptin while performing an osmotic stimulation with infusion of hypertonic saline.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to 90 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •age > 18 years,
  • •hyponatremia < 132 mmol/L

Exclusion Criteria

  • •age < 18 years
  • •cerebral metastases
  • •serum sodium > 132mmol/L

Investigators

Sponsor
University of Wuerzburg
Sponsor Class
Other

Study Sites (1)

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