Subclassification of the Syndrome of Inappropriate ADH Secretion

Completed

• Conditions: Hyponatremia

• Registration Number: NCT01341665
• Lead Sponsor: University of Wuerzburg

Brief Summary

The aim of this study is to evaluate the different types of osmotic dysregulation in patients with Syndrome of Inappropriate ADH (SIADH) and, hence, to analyze the pathophysiology of SIADH.

These types will be characterized by measurement of AVP and copeptin while performing an osmotic stimulation with infusion of hypertonic saline.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-03
• Status Verified: 2011-04
• Primary Completion: 2011-04
• Study Completion: 2011-04
• Study First Submitted: 2011-04-21
• Study First Submitted QC: 2011-04-25
• Last Update Submitted: 2011-04-25
• Study First Posted: 2011-04-26
• Last Update Posted: 2011-04-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• age > 18 years,
• hyponatremia < 132 mmol/L
• SIADH

Exclusion Criteria

• age < 18 years
• cerebral metastases
• serum sodium > 132mmol/L

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

University of Wuerzburg; 🇩🇪 Wuerzburg, Bavaria, Germany