NL-OMON31488已完成不适用
Effects of the norepinephrine reuptake inhibitor reboxetine on the exploitation-exploration trade-off - Norepinephrine and exploitation/exploration
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Healthy volunteers between 18 and 25 years of age.
- •Volunteers are willing to give written informed consent to participate in the study and to comply with the study procedures.
- •Participants should speak Dutch fluently.
- •Normal or corrected-to-normal vision.
排除标准
- •Clinically significant abnormal values for clinical chemistry, haematology or urinalysis at screening.
- •Clinically significant abnormal physical examination, vital signs or 12-lead ECG at screening.
- •Clinically significant (history of) psychiatric illness.
- •Clinically significant (history of) major internal or neurological illness.
- •Use of psychotropic medication.
- •Alcohol or substance abuse.
- •Pregnancy or breast feeding.
- •Positive urine screen for drugs of abuse.
- •Clinically significant acute illness within 7 days prior to study drug administration.
- •Clinically significant history of food and/or drug allergies.
- •Serology positive for hepatitis B surface antigen, hepatitis C antibodies or HIV antibodies.
- •Have received an experimental drug or used an experimental medical device within 90 days before the planned start of treatment.
- •Psychological and/or emotional problems which would render the informed consent invalid, or limit the ability of the subject to comply with the study requirements.
- •Donation of 1 or more units (approximately 450 ml) of blood or acute blood loss of an equivalent amount of blood within 90 days before the planned treatment.
- •Exposure to any medication, including over-the-counter medication (not including paracetamol), within 2 weeks prior to treatment.
- •Subject not able to refrain from alcohol from 10 PM the night prior to the experimental session until end of the study day.
- •Subject not able to refrain from smoking from 10 PM the night prior to the experimental session until end of the study day.
- •Subject not able to refrain from xanthine intake from 10 PM the night prior to the experimental session until end of the study day.
- •Subject not able to refrain from grapefruit intake from 14 days prior to the experimental session until end of the study day.
- •Subject not able to refrain from heavy physical exertion from 24 hours prior to the experimental session until end of the study day.
研究者
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