Comparison of intravenous ketamine with propofol versus ketamine with dexmedetomidine for procedural sedation in upper GI endoscopy

For this study elective  patients for Upper GI endoscopy will be divided in 2 groups for procedural sedation .1 group will be receiving intravenous ketamine with propofol for sedation and the 2nd group will be receiving  ketamine with dexmedetomidine for sedation .Both the groups will then be compared for haemodynamic changes - blood pressure and pulse and Ramsay sedation score and recovery time .ketamine will be the base drug and will be given in a dose of 1 mg/kg  .propofol will be given in a dose of 1 mg/kg  and  a maintenance dose of 0.25 mg/kg while  dexmedetomidine will be given in a dose of 0.5 mcg/ kg and a maintenance dose of 0.1 mcg/ kg .

In case adequate sedation is not achieved ketamine will be given in dose of 0.25 mg/ kg . Patients in both groups will also be assessed for recovery time along with Ramsay sedation score and haemodynamic changes.