Comparative evaluation of two drug combinations of propofol-ketamine and propofol-fentanyl for total intravenous anaesthesia in short surgical procedures

Phase 2

Recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2019/06/019790
• Lead Sponsor: Kalinga institute of medical sciences

Brief Summary

In this study a combination of propofol with ketamine is compared with a combination of propofol with fentanyl in patients undergoing total intravenous anaesthesia for elective surgeries of less than 60 minutes duration. Hemodynamic parameters, time to recovery, depth of sedation, incidence of post operative nausea vomiting and time to rescue analgesics are compared

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-07
• Last Update Posted: 2020-08-07

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Patients belonging to ASA 1 and 2 posted for elective surgical procedures lasting for less than 60 minutes, not requiring a difficult airway.

Exclusion Criteria

Patients belonging to ASA 3 4 History of allergy to any particular drug used in the study History of egg allergy History of opioid or substance abuse.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the hemodynamic and respiratory parameters in the intra operative period.	To compare the hemodynamic and respiratory parameters in the intra operative period.

Secondary Outcome Measures

Name	Time	Method
To study the incidence of post operative nausea vomiting, depth of sedation, time to discharge from the PACU, and total dose of study drugs used	Every 15 min from shifting the patient to PACU , till discharge from PACU

Trial Locations

Locations (1)

Kalinga institute of medical sciences; 🇮🇳 Khordha, ORISSA, India

Kalinga institute of medical sciences

🇮🇳Khordha, ORISSA, India

Dr Aparna Jayaraj

Principal investigator

8547489033

draparnajayaraj91@gmail.com